Dr. Brett HemricGarcia, Thalia2023-04-202023-04-202023-04-19Garcia, Thalia. “Enantioselective Aziridinium/Fluoronium Ion Formation Using Lewis Base Catalysis.” Honors Program, The University of Tampa, 2023. https://doi.org/10.48497/FD3B-5182.http://hdl.handle.net/20.500.11868/3914Recommended citation: Garcia, Thalia. “Enantioselective Aziridinium/Fluoronium Ion Formation Using Lewis Base Catalysis.” Honors Program, The University of Tampa, 2023. https://doi.org/10.48497/FD3B-5182.Efforts toward establishing the concept of enantioselective Lewis base catalysis with nitrogen sources is reported. This project seeks to address challenges in alkene amination chemistry by developing diastereo-, enantio- and regioselective addition of nitrogen to alkenes using Lewis base catalysis to provide advances to the stereoselectivity shortcomings of current approaches. Furthermore, due to the unprecedented exploration of using non-hypervalent Row 2 electrophiles in Lewis base catalysis, this research offers the potential for groundbreaking innovation in this field. This report details the investigation of different nitrogen substrates, Lewis base catalysis, and nucleophiles in varied alkene systems to determine the potential synergy in doing an alkene amination through Lewis base catalysis.en-USNitrogenLewis base catalysisAlkene difunctionalizationThesishttps://doi.org/10.48497/FD3B-5182